As highly hydrated liposome-based therapies, Liposphere’s products can be used to reduce joint pain and improve mobility, while their spherical structure also carries the potential of encapsulating active pharmaceutical ingredients for delivery of medication to areas that are difficult to reach.

Liposphere’s liposome-based platform technology, CCoat®, also carries the potential to be applied to synthetic medical surfaces such as orthopaedic implants, aiming to smooth movement in a wide range of conditions.

Introducing our unique product
The platform technology CCoat® by Liposphere

We developed CCoat® as an intraarticular injectable device for use in patients with knee osteoarthritis. Preclinical (in vitro and in vivo) studies demonstrated that CCoat is a biocompatible device that forms a coating layer over the cartilage surfaces of the opposing bones within the knee joint. The effects on lubrication and reduction of surface wear were observed under nonclinical test conditions and are not presented as demonstrated clinical performance outcomes.
Based on its liposome nature, CCoat® functions as a biocompatible joint therapy, yet these lipid spheres also provide a vehicle for encapsulating active pharmaceutical ingredients or supplements to be delivered to the body.
Additionally, CCoat’s liposome-based technology may be applied to artificial medical surfaces such as implants, catheters, hydrogels and needles, aiming to support low friction and improved functionality while surfaces slide against each other.

Artificial surfaces – PIPELINE PRODUCT

With the product line SCoat (Investigational Device), Liposphere develops lipid-based technologies to provide highly lubricious interfaces for artificial surfaces relevant in different healthcare applications. Liposphere has recently conducted pilot studies with commercial partners to assess SCoat on different materials used for artificial joint implants.

// Applying liposome-based materials to artificial surfaces