Welcome
Liposphere –
where
Biolubrication starts

Liposphere is a biomedical start-up spun out from the Weizmann Institute of Science (Israel) in early 2019. Its unique IP-protected platform technology of unmatched biolubricants has been developed over the past two decades at the Department of Materials & Interfaces under Professor Jacob Klein. Based on the profound knowledge of Klein and his team, Liposphere is now developing an innovative platform of highly lubricious, water-based biocompatible nanomaterials -named AqueousTech– for conditions in or in interaction with the human body where ultralow friction is crucial. 

Office:        +972 (0) 8 – 616 0500
E-Mail:      

„Answering unmet medical needs“

There is an urgent, global, unmet medical need to develop innovative solutions, which can sustain forces within mechanically stressed environments. In the context of the human body, the major synovial joints such as the knee a or hip joint articulate under high-load conditions, whereas the cornea/eye lid interface for example is exposed to high shear stresses under low loads. Both scenarios when physiologically impaired are the exact pain points where Liposphere’s formulations can play a crucial role.

 

Liposphere’s formulation can be used as a pure lubricant, but also has the potential to encapsulate active pharmaceutical ingredients in the future, for delivery of pharmaceuticals to targets that currently are difficult to reach. In addition, Liposphere’s platform technology enables the coating of artificial medical surfaces such as catheters and protheses, giving the potential for smooth movement in a wide range of biomedical devices.

 

Investors
„You are looking for an investment
with
high potential growth? Join us
and
be part of our innovative vision.“

Introducing our unique product
The platform technology  AqueousTech

 

Liposphere’s platform technology AqueousTech can be used as a pure lubricant to coat biological surfaces, but also provide the vehicle to encapsulate active pharmaceutical ingredients or supplements and to deliver these to targets that currently are difficult to reach.

In addition, Liposphere’s platform technology enables the robust coating of artificial medical surfaces such as catheters, hydrogels and needles, leading to ultra-low friction and improved lubrication when coated surfaces slide past each other in an aqueous system.

 

Biological surfaces

We develop AqueousJoint (Investigational Device) as an intra-articular injectable for the treatment of knee Osteoarthritis. AqueousJoint acts as a biocompatible, boundary lubricant coating the cartilage surfaces of the opposing bones of the knee joint, hence reducing friction and wear by providing superior lubrication.

// Reducing friction significantly by protecting cartilage

 

 

AqueousEye (Investigational Device) is a topical biolubricant under development for patients, who suffer from mild to moderate Dry Eye Syndrome. The formulation hydrates and lubricates the cornea and aims to prolong retention time.

// Treating Dry Eye Syndrome efficiently

Artificial surfaces

With the product line AqueousSurface (Investigational Device), Liposphere develops highly lubricious coatings for artificial surfaces relevant in different healthcare applications. Liposphere is currently conducting and establishing pilot studies with distinct commercial partners in the catheter and contact lens manufacturing sector.

// Coating artificial surfaces with ultra-low friction materials

News from Liposphere

16
Oct
Published in Science!
Liposphere’s technology published in Science Magazine!

Congratulations to Prof Jacob Klein, Ronit Goldberg and team for this remarkable achievement! Enjoy the read!

https://science.sciencemag.org/content/370/6514/335

15
Sep
IIA funding approval 2020/2021!
The Israel Innovation Authority (IIA) supports the development and commercialization of Liposphere’s orthopaedic product AqueousJoint!

Within the upcoming year, we will complete the preclinical experiments and ultimately manufacture cGMP batches in-house for First-In-Human studies. Therefore, we are setting up a new facility to fulfill this task according to the required standards.

18
Aug
Progress AqueousJoint
AqueousJoint’s preclinical safety data encourages!

We successfully accomplished a first production of our orthopaedic product AqueousJoint after design-freeze earlier this year. We have started preclinical experiments with this formulation and are beginning to see promising results!

 

 

 

 

 

 

 

 

Social News
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There is always exciting progress and news in our field of development and we are proud to be part of this dynamic process of shaping our future together. If you want to be part of this exciting journey and want to know today everything, that is new tomorrow, join us on LinkedIn!

 

     

Contact us

Would you like to contact us? Call us or send us a message
using the contact form – looking forward to hearing from you.

 

Liposphere Ltd.
Pinhas Sapir 3
1st Floor @ Daren Labs
Ness Ziona 7403626, Israel

Office:  +972 (0) 8 – 616 0500
E-Mail:  


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