Liposphere presented its AqueousJoint knee joint injectable at the Alliance for Advanced Therapies in Orthopedics (ATiO, https://atioalliance.org/) conference in Berlin. Following competitive rounds of presentations, the Company won the Best Early-Stage Company award judged by a high-profile orthopedic audience and received the „Dancing Bear“ trophy.
Creating values and growth
Are you interested in being part of this unique venture?
The Israel Innovation Authority (IIA) and various investors are! Liposphere is supported via the IIA’s Women’s Entrepreneur Track in order to accelerate the commercialization of our intra-articular injectable to treat Osteoarthritis. Moreover, we are very proud to have an outstanding network of investors behind us to join forces to accomplish our vision and to be able to explore AqueousTech’s potential in the context of different markets.
The great strength of the technology based on its platform opportunities and innovative nature as such is highly valued among investors and hence de-risks investments.Office: +972 (0) 732113227
Innovations heading for
Efficient water-based biolubricants are of need in a large number of technological and medical market segments. With the focus on the orthopaedic, ophthalmic and coating sector, we intend to penetrate highly mature, competitive, but growing markets.
The growth of the orthopaedic injectable market is driven by an increase in the geriatric population and longer life spans. The major drivers of the Dry Eye market over the next years are more urbanized living conditions with rising use of computers, novel pipeline drugs and better disease awareness leading to increased diagnosis and treatment rates.
Global annual market size by
*Source: Lubricants Market Size, Share & Trends Anylysis Report By Product 2019-2025; Grand View Research
Our strategic business areas
current market-approved solutions
Liposphere is a young, dynamic company with massive innovation potential originating from its IP-protected platform technology of unmatched water-based lubricants. In-vitro, on surfaces, Liposphere’s basic formulation outperforms hyaluronic acid-based solutions dramatically (by 2-3 orders of magnitude) in terms of lubrication capability (7). In animal experiments conducted so far, AqueousTech has been shown to be safe to use. Moreover, with respect to the orthopaedic application, AqueousJoint demonstrated a massively prolonged retention time in animals following intra-articular injection compared to current solutions on the market.
„We believe that AqueousTech
has the potential to revolutionize the
market of waterbased lubricants“
Taken together, our deep scientific expertise and experience in product development in combination with a tremendously strong advisory and support from the Israel Innovation Authority give Liposphere a very unique position for the upcoming years!
News from Liposphere
The Israeli Ministry of Health approved our efficacy-focused clinical trial protocol. The trial will be a multi-center, double-blinded, and randomized study, and the primary outcome is to show the superiority of the AqueousJoint product compared to a saline solution (Placebo). Moreover, low, and high dosages of AqueousJoint will be used to identify the optimum product concentration.
Each group will recruit 50 patients to achieve statistically meaningful results.
The first clinical site in Assuta Hospital, Ashdod, was initiated. Further sites are Kaplan Hospital, Rehovot, Tel-Hashomer, Ramat-Gan, and Asaf Harofe Beer-Yacov, which will open soon to expedite recruitment.
20 Patients with diagnosed Osteoarthritis were enrolled in our First-In-Human safety trial in which the AqueousJoint product was clinically evaluated for the first time. Those patients received a single AqueousJoint injection into their knee joint cavity.
A follow-up time of 6 months was completed successfully, confirming the product’s safety (no related adverse events reported) and a long-lasting pain reduction effect of 6 months. The efficacy output was assessed using standardized questionnaires: The Knee Injury and Osteoarthritis Outcome Score (KOOS) and a Numeric Visual Scale (NVS) measure.
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There is always exciting progress and news in our field of development and we are proud to be part of this dynamic process of shaping our future together. If you want to be part of this exciting journey and want to know today everything, that is new tomorrow, join us on LinkedIn!
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Office: +972 (0) 732113227