CCoat® by Liposphere
Introducing our platform technology
CCoat® by Liposphere physically adsorbs biological as well as artificial surfaces to form a robust coating layer with extremely effective lubrication for interfaces as they slide past each other. This layer can protect surfaces from wear and tear under mechanical stresses as well as be applied as a pure surface coating device or combined drug delivery/lubrication vehicle.
CCoat® is composed of lipid bilayers, which form stable and durable 3D spheres (liposomes), while exposing conjugated zwitterionic polymers at their surface in an aqueous environment. These zwitterionic polymers allow for the structural stabilization of the liposomes, but also provide together with the properties of the lipid head groups as such the actual components for superior hydration and hence lubrication.
Liposphere’s products are capable of lowering high tear and wear forces by 3-5 orders of magnitude as scientifically shown (5). They formulations have been proven stable and homogeneous at room temperature over a long period of time. In-vitro, the survival of different cell types after exposure to CCoat® fulfils biocompatibility and safety requirements under ISO guidelines.
We develop unique biomaterials that reduce
friction and wear efficiently the body
Our innovation at a glance
Liposphere‘s current applications
Reducing wear to enable smooth motion
Liposphere’s patented
joint articulation injectable
CCoat® (Investigational Device) is targeted at coating the knee joint’s cartilage surface, providing a long-lasting mechanical “cushion” to enable ease of movement.
This cushioning function is achieved by utilizing robust yet elastic lipid-based spheres. These spheres hold surrounding water in a unique way, which in combination with their 3D morphology, offers high lubrication during joint articulation.
Contact us
Would you like to contact us? Call us or send us a message using the contact form – looking forward to hear from you.